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RESOLVING IMMUNE CELL DYNAMICS

USING MICROCHIP TECHNOLOGIES


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We are happy to share the latest work led by PhD student Quentin Verron in our team.


Turns out that NK cells recognize large protein patterns when building synapses and mobilizing the cytotoxic machinery but need receptor engagement at the site of degranulation.


Have a look at the full manuscript over at bioRxiv:

Link: NK cells integrate signals over large areas when building immune synapses but require local stimuli for degranulation

Capture of perforin released by an NK cell forming a complete contact on dot-shaped ⍺LFA-1 + ⍺CD16 AIS

Capture of perforin released by an NK cell forming a complete contact on donut-shaped ⍺LFA-1 + ⍺CD16 AIS

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KTH, SciLifeLab
Önfelt Lab, Biophysics, Gamma 3 
Tomtebodavägen 23A
SE-171 65 Solna
Sweden

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