Welcome to the ÖNFELT LAB
We are happy to share the latest work led by PhD student Quentin Verron in our team.
Turns out that NK cells recognize large protein patterns when building synapses and mobilizing the cytotoxic machinery but need receptor engagement at the site of degranulation.
Have a look at the full manuscript over at bioRxiv:
Capture of perforin released by an NK cell forming a complete contact on dot-shaped ⍺LFA-1 + ⍺CD16 AIS
Capture of perforin released by an NK cell forming a complete contact on donut-shaped ⍺LFA-1 + ⍺CD16 AIS
Önfelt Lab, Biophysics, Gamma 3
SE-171 65 Solna